![]() Hypocapnia abolished phasic activity and unmasked its tonic component in vagotomized cats. Vagotomy eliminated these static lung volume effects and increased spontaneous cyclic activity. Lung inflation inhibited phasic pharyngeal constrictor activity to reveal its tonic component lung deflation eliminated both phasic and tonic components. ![]() In eupnea, pharyngeal constrictor exhibited tonic and expiratory phasic activity. However, clinical parameters are also important and should be included in future prospective trials.read more read lessĪbstract: The electromyogram of the middle pharyngeal constrictor muscle and the electroneurogram of the phrenic nerve was recorded in parallel with measurements of tidal inspiration and tracheal airflow in chloralose-urethane anesthetized cats. Conclusion These findings motivate further efforts to reduce the dose to the swallowing structures, especially to the pharyngeal constrictor muscles and the larynx. Only this last factor significantly correlated with late dysphagia at multivariate analysis. The volume of the middle pharyngeal constrictor muscle receiving ≥50 Gy ( p = 0.04), the mean dose to this structure ( p = 0.02) and to the supraglottic larynx ( p = 0.04) were significantly associated with late swallowing problems at univariate analysis, along with tumor localization ( p = 0.008), T-classification ( p = 0.02), and pretreatment swallowing problems ( p = 0.01). Swallowing was evaluated by four quality-of-life questionnaires: EORTC C30 and HN mean follow-up was 20.4 months (range, 6–45 months). Methods and Materials Consecutive patients, treated with radiotherapy (70–72 Gy) and concomitant chemotherapy (cisplatinum 100 mg/m 2 every 3 weeks) between 20, were examined. ![]() Abstract: Purpose To evaluate late dysphagia after chemoradiotherapy for locally advanced head-and-neck squamous cell carcinoma, and to examine its correlation with clinical and dosimetric parameters. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |